1.Consider the following statements regarding CRMA-1001, recently in the news:
Which of the statements given above are correct?
Statement 1 – Correct:
CRMA-1001 is an epigenetic editing therapy being investigated for chronic Hepatitis B. It is intended to achieve a potential functional cure by silencing persistent HBV genetic material.
Statement 2 – Correct:
The therapy works by methylating viral DNA, thereby switching off or silencing the viral genetic material. Importantly, the approach is intended to avoid modifying the host's genetic code.
Statement 3 – Correct:
This distinguishes CRMA-1001 from conventional CRISPR-Cas9 approaches. Cas9 generally creates double-strand DNA breaks, after which cellular repair mechanisms can disrupt or modify the targeted sequence. CRMA-1001 instead seeks to produce a durable epigenetic change without cutting the DNA.
2.Consider the following statements regarding the Himalayan Yak Festival:
Which of the statements given above are correct?
Statement 1 – Correct:
The Himalayan Yak Festival celebrates the cultural traditions, livelihood practices and importance of yak-rearing communities in the Himalayan region.
Statement 2 – Correct:
Sikkim is an important region for yak husbandry in India. Yaks are particularly associated with the high-altitude areas of the state.
Statement 3 – Correct:
The yak (Bos grunniens) is specially adapted to cold and high-altitude environments. It provides milk, meat, fibre and transport support and is an important livelihood resource for Himalayan pastoral communities.
Statement 4 – Incorrect:
Yaks are not tropical-lowland animals. They are adapted to cold, mountainous and high-altitude environments. In India, they are mainly associated with the Himalayan and trans-Himalayan regions.
3.Consider the following statements regarding the Bihar Museum:
Which of the statements given above are correct?
Statement 1 – Correct:
The Bihar Museum is located in Patna, Bihar. It is a major museum showcasing Bihar's rich archaeological, historical and cultural heritage.
Statement 2 – Correct:
According to the given current-affairs information, Bihar Museum was ranked 9th globally and 1st in Asia in the World’s 100 Best Museums 2026 list published by Worth a Journey, a Munich-based travel guide and magazine.
Statement 3 – Correct:
Bihar Museum was reported to be the only Indian museum to feature in the global list of the 100 best museums.
Statement 4 – Correct:
Bihar Museum's 9th position placed it above the Metropolitan Museum of Art (The Met), New York, ranked 10th, and the Louvre Museum, Paris, ranked 31st.
4.Consider the following statements regarding the Order of Zayed II, recently in the news:
Which of the statements given above are correct?
Statement 1 – Correct:
The Order of Zayed II is a prestigious UAE state honour. It is named after Sheikh Zayed bin Sultan Al Nahyan, the founding father and first President of the UAE.
Statement 2 – Correct:
Indian Captain Smit Machchhar, along with fellow flydubai crew members, received the First Class of the Order of Zayed II.
Statement 3 – Correct:
The honour recognised their bravery and exceptional efforts to safeguard passengers during a mid-air attack.
Statement 4 – Correct:
The award was conferred by Sheikh Mohamed bin Zayed Al Nahyan, the President of the UAE.
5.Consider the following statements regarding the Tobacco-Free Youth Campaign 4.0 (TFYC 4.0):
Which of the statements given above are correct?
Statement 1 – Correct:
Tobacco-Free Youth Campaign 4.0 (TFYC 4.0) is a 60-day nationwide initiative launched by the Ministry of Health and Family Welfare (MoHFW), Government of India.
Statement 2 – Correct:
The campaign is being undertaken in collaboration with the Ministry of Education and MY Bharat, thereby involving both the education system and youth-oriented platforms.
Statement 3 – Correct:
A key objective is to prevent the initiation of tobacco and nicotine use among children and adolescents. It also encourages cessation among existing users.
Statement 4 – Incorrect:
The campaign is not limited to awareness generation. It also seeks to strengthen enforcement of tobacco-control laws and promote tobacco-free campuses and communities.
