- About half of the world's population is now at risk of dengue with an estimated 100–400 million infections occurring each year.
- The incidence of dengue has grown dramatically around the world in recent decades, about 5.2 million cases in 2019.
- The highest number of dengue cases was recorded in 2023, affecting over 80 countries in all regions of WHO.
- It resulted in a historic high of over 6.5 million cases and more than 7300 dengue-related deaths reported.
- Factors for increasing risk of spread – The changing distribution of the vectors (chiefly Aedes aegypti and Aedes albopictus mosquitoes), especially in previously dengue naïve countries.
- The consequences of El Niño phenomena in 2023 and climate change leading to increasing temperatures and high rainfall and humidity.
- Fragile health systems in the midst of the COVID-19 pandemic.
- The political and financial instabilities in countries facing complex humanitarian crises and high population movements.
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